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The research lab of Dr. Michael Holinstat in the Department of
Pharmacology at the University of Michigan, Ann Arbor, MI is in
search of a postdoctoral Research Fellow. As the selected candidate
you will investigate platelet biochemical and physiological steps
in the regulation of blood coagulation in vitro, ex vivo, and in
vivo in human and animal models of blood clotting. You will be
afforded the ability to work in an open-lab environment with access
to all of its state-of-the-art equipment in order to gain a greater
understanding of hemostasis and thrombosis in the in vivo, in
vitro, and ex vivo setting in both human and small animal
The lab maintains state-of-the-art hemostasis and thrombosis
facilities including full protein chemistry capabilities,
lumi-aggregometers, flow cytometer, hemavet, a microscopy facility
containing 2 zeiss microscopes with the capacity for in vivo
intravital confocal microscopy and single-cell high resolution
microscopy, PCR machines, 2 multi-mode plate readers,
thromboelestography, and a phlebotomy suite with full-time
phlebotomist. The lab is situated in the heart of Michigan Medicine
within steps of a multitude of research resources and easy access
to collaborators, the clinics, and animal facilities.
Michigan Medicine improves the health of patients, populations
and communities through excellence in education, patient care,
community service, research and technology development, and through
leadership activities in Michigan, nationally and internationally.
Our mission is guided by our Strategic Principles and has three
critical components; patient care, education and research that
together enhance our contribution to society.
Why Join Michigan Medicine?
Michigan Medicine is one of the largest health care complexes in
the world and has been the site of many groundbreaking medical and
technological advancements since the opening of the U-M Medical
School in 1850. Michigan Medicine is comprised of over 30,000
employees and our vision is to attract, inspire, and develop
outstanding people in medicine, sciences, and healthcare to become
one of the world's most distinguished academic health systems. In
some way, great or small, every person here helps to advance this
world-class institution. Work at Michigan Medicine and become a
victor for the greater good.
What Benefits can you Look Forward to?
- Excellent medical, dental and vision coverage effective on your
very first day
- Retirement Savings Opportunities
As the selected candidate the project you will focus on is the
regulation of platelets in health and cardiovascular disease. In
particular, elucidating the key intraplatelet signaling pathways
that regulate platelet activation which ultimately leads to
myocardial infarction (MI) and stroke. You will determine the
importance of these pathways in the regulation of
platelet-dependent blood clotting and thrombosis using human
platelet studies ex vivo and mouse models in vivo.
A PhD in pharmacology, physiology, biochemistry, molecular
biology, or other related biomedical discipline.
In order to be considered for this position, the applicant must
have met or will have met all the required qualifications prior to
the start date of employment.
- Experience working with small animals.
- Experience with flow cytometry, western blot techniques and
other biochemical assays.
- Working in a team environment.
Michigan Medicine conducts background screening and
pre-employment drug testing on job candidates upon acceptance of a
contingent job offer and may use a third party administrator to
conduct background screenings. Background screenings are performed
in compliance with the Fair Credit Report Act. Pre-employment drug
testing applies to all selected candidates, including new or
additional faculty and staff appointments, as well as transfers
from other U-M campuses.
Job openings are posted for a minimum of seven calendar days.
The review and selection process may begin as early as the eighth
day after posting. This opening may be removed from posting boards
and filled anytime after the minimum posting period has ended.
U-M EEO/AA Statement
The University of Michigan is an equal opportunity/affirmative
Research Fellow for Platelet Signaling Study
Ann Arbor Campus
Ann Arbor, MI
MM Pharmacology Department
2/04/2021 - 6/04/2021