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Post-Doctoral Associate: In Vitro Preclinical Oncology

Company: Covance
Location: Ann Arbor
Posted on: June 8, 2021

Job Description:

Job Overview:

Post-Doctoral Associate: In Vitro Preclinical Oncology

Company Overview

Covance by Labcorp, a business segment of Labcorp, is recognized as a leader in drug development, medical device, diagnostics, crop protection and chemical testing because of our exceptional people. We embrace and celebrate the different strengths, experiences and perspectives of our nearly 65,000 enterprise team members across the globe. Our team is driven by our mission to improve health and improve lives. Here, you can play a role in bringing new scientific discoveries to life and make a difference in the lives of millions. And, with our comprehensive service portfolio, you'll have the opportunity to explore diverse projects and unique career paths across life science.

Global Post Doc Development Program

Exciting Opportunity to be part of the Covance by Labcorp Post Doc Development Program at our Ann Arbor, MI location and apply your postdoc in an industry role.

Uniquely positioned as a world leader in drug development, we've crafted complex and cutting edge projects specifically for motivated postdocs who want to explore research in industry.

Postdocs hired into our program will also participate in a tailored learning and development journey designed to expand technical expertise, professional and leadership development and networking opportunities. The technical pillar of your learning journey includes regulatory training, such as GLP, conference attendance, publication opportunities and dedicated mentorship. Additionally, you'll be part of leadership courses, executive speaker series, career exploration weeks and presentation opportunities with senior scientific leaders.

Don't miss this unique opportunity to apply your postdoc skills and experiences in an industry project with dedicated learning and development to support your scientific, research and professional career aspirations. Join us and take pride in delivering scientific work that helps save the lives of millions of people around the world!

About Team:

The In Vitro Operations Team at Covance by Labcorp Preclinical Oncology consists of 21 members with a vast amount of experience in cell culture, cell-based in vitro assays, molecular and biochemical in vitro assays, flow cytometry, immunohistochemistry, and CAR T cell manufacturing. The Team works closely with the In Vivo Operations Team to coordinate client study execution and the Scientific Development Team to coordinate sales and marketing strategies. One of the main focuses of the In Vitro Operations Team is to continually develop and use new technologies and techniques to help our clients efficiently advance through the preclinical stages of their research.

Project Summary:

  • Investigate immuno-oncology profiles of various human and mouse cancer models using nCounter Gene Expression Panels, GeoMx DSP RNA Assays, and/or GeoMx DSP Protein Assays to help clients understand tissue heterogeneity and answer key biological questions using tumor models
  • Investigate existing or novel biomarkers in these models and how the tumor microenvironment can influence them
  • Execute in vivo and in vitro studies with in-demand tumor models to develop internal scientific capabilities and collateral
  • Study regions of interest within tumors under varying treatment conditions and standards of care to determine the interactions between the tumor, infiltrates, and the microenvironmen
  • Develop expertise in data analytics to generate tailored solutions for visualizing cancer heterogeneity and characterization of signaling pathways in response to targeted therapies
  • Author white papers or publications of results that can drive expanded use of in vitro models as predictors of in vivo response and the associated marker profile that accompanies this

Education/Qualifications:

Education/Qualifications/Skills:

  • Ph.D. in Chemistry, Biology, Biochemistry or related scientific area
  • Experience in one or more of the following scientific areas is desired

o Genomics/Proteomics

o Biomarkers

o Cancer Biology

o Immunology

o Histology

o Immunohistochemistry

Experience:

Physical Demands and Work Environment:

  • Works in a research environment with exposure to sharps, caustic chemicals, and substances of unknown hazard.
  • Must function and adequately perform all responsibilities associated with the job while adhering to various established safety and PPE (Personal Protective Equipment) requirements
  • Ability to lift 50 pounds and bend and move within small spaces.
  • Regularly works with animal tissues with risk of exposure to allergens, zoonotic diseases and biohazards.
  • Laboratory is BioSafety Level II.

Keywords: Covance, Ann Arbor , Post-Doctoral Associate: In Vitro Preclinical Oncology, Other , Ann Arbor, Michigan

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